Top 5 Week 1 College Football Games to Bet On

Top 5 Week 1 College Football Games to Bet On

Quick Tips:

For college football betting enthusiasts, we’re less than two weeks out from the start of the season. After a brief appetizer on Saturday, August 25, the real fun begins five days later as we move into the full slate of games in Week 1.

There are some blockbuster matchups to start the season, including a number of important non-conference tilts. Here are the five can’t-miss games to bet on in Week 1, with odds from William Hill.

  1. Virginia Tech vs Florida State

    This is the best conference game in Week 1, a high-pressure ACC showdown between the Hokies of the ACC Coastal Division and the Seminoles of the ACC Atlantic. The big story here is that Willie Taggart makes his FSU coaching debut after replacing national championship-winning coach Jimbo Fisher, who left for Texas A&M.

    Taggart has a good, but “good” is not the normal standard at Florida State. Greatness is expected there. Therefore, this is might be a season which doesn’t fulfill Seminoles fans’ dreams. Both teams’ quarterback situations are sources of intrigue.

    Both teams struggled on offense last year and only figure to improve. However, both defenses only return three starters. Don’t be surprised if this leads to a higher scoring affair than most are expecting on Labor Day.

    The play here is taking the Over of 52.

  2. Miami vs LSU

    The sense of uncertainty surrounding LSU football is hard to avoid. The Tigers have undergone a lot of changes on their coaching staff, and head coach Ed Orgeron – who took a very hands-on approach to last year’s team – seems to want a power running game and a simplified approach that emphasizes toughness and muscle.

    That might not be the way to attack a Miami defense that was extremely successful at forcing turnovers last season. The Hurricanes passed around a “turnover chain” on the sidelines after each fumble recovery or interception. They made a habit out of taking the ball away from the opposition.

    LSU’s offense will need to be precise and crisp in order to avoid giving Miami the handful of mistakes that could change the complexion of this game. Miami’s offense is not expected to do much against LSU’s defense, but LSU’s offense will face even more pressure when this game begins.

    The play here is taking the Under of 45.5.

  3. Auburn vs Washington

    This game is in Atlanta, which will give Auburn a partisan crowd. It is a game that will be very attractive because it matches two veteran quarterbacks, Jake Browning of Washington and Jarrett Stidham of Auburn. More importantly, both teams have realistic aspirations of making the College Football Playoff.

    Washington plays mostly a cupcake schedule, so it needs to show well here if it wants to make the national semifinals. On the other hand, Auburn has such a tough schedule that a Week 1 loss might sink them. With upcoming road trips to Mississippi State, Georgia and Alabama, the Tigers surely suffer more than one loss.

    While Auburn has an excellent quarterback, Washington might have the best secondary in the country. Auburn also has a young offensive line, which could be the deciding factor. This is very possibly the biggest game of them all in Week 1, but look for Washington to cover and win outright.

    The play here is Washington +2.5.

  4. West Virginia vs Tennessee

    This game will make national news because it will mark the head coaching debut of Jeremy Pruitt. The Tennessee coach used to be a defensive coordinator at multiple SEC schools – Georgia and Alabama – before making the jump to the big seat with the Vols.

    Pruitt leads a Tennessee team that bottomed out last year in the final season under embattled coach Butch Jones. Tennessee does not have much of an offense but could be solid on defense.

    West Virginia owns one big advantage in this game: It has a veteran quarterback with NFL-level talent. Will Grier is among the best quarterbacks in the nation, and NFL scouts will be salivating to get an early look at him.

    If this contest were in Tennessee at Rocky Top, maybe the Vols could pull an upset. At a neutral site in Charlotte, look for West Virginia’s passing game to be the reason why they pull away.

    The play here is West Virginia -10.

  5. Michigan vs Notre Dame

    The focal point in this game will be Michigan quarterback Shea Patterson, the transfer from Ole Miss who could be Michigan’s best quarterback in the Jim Harbaugh era. Michigan has struggled to get great quarterback play under Harbaugh, a central reason the Wolverines have failed to reach expectations under their very visible head coach.

    If Patterson has a big year, that could all change, and his first big test comes in Notre Dame Stadium against the Fighting Irish, who were in the national championship hunt entering November last season but lost to Miami and Stanford to drop out of the College Football Playoff picture.

    There’s finally a little heat under Harbaugh’s seat as he has to start delivering in these types of games. With Patterson under center and a terrific defense backing him up, look for Michigan to finally earn a signature win for Harbaugh.

    The play here is taking Michigan -2.

Recommended Betting Sites

shield of trust Secure trusted partners Trusted star verified Verified
  1. Place £10, Get £40 in Free Bets + £10 on Casino
    Promo Code: 10FREE

  2. EXCLUSIVE: Bet £15, Get £10

  3. Get up to £100 in Bet Credits!

  4. Bet £10, Get £10 Free Bet

    18+ New Players only. For free bet wagering requirements and minimum odds read T&C’s. Terms Apply New players only. The qualifying bets to claim the Free Bet must have minimum odds of 3/1 (4.00) or higher and must be settled before triggering free bet. 18+. - Full Terms Apply Visit Site
  5. Bet £10 Get £20

    18+ New Players only. For free bet wagering requirements and minimum odds read T&C’s. Terms Apply The Promotion operates as a £/€20 Surprise Bet when you place a bet of at least £/€10 on any market with odds greater than or equal to 1.50 as your first bet. The Promotion runs from 09/08/2021 / 12:00 (BST) until 31/12/2021 / 12:00 (BST) (the “Promotional Period”). The Promotion is only valid to: (a) new customers; (b) customers aged 18 years or over. To qualify for the Promotion, participant must deposit and place a £/€10 bet as their first bet on any market (excluding each way) in the sportsbook with odds greater than or equal to 1.50. Only original odds count toward the promotion. Supercharged odds do not count towards the promotion. An accumulation of smaller stakes will not count. Cashed out bets do not count towards this promotion. Only available once per customer. Rewards will be credited to qualifying participants within 48 hours after placing the qualifying bet. Potential winnings from the Surprise Bet are paid in withdrawable cash, excluding the stake. This offer cannot be used in conjunction with any other offer. Visit Site
  6. Welcome bonus bet £10 Get £15

  7. Bet £10, Get £10 + 50 Extra Spins

  8. Bet £10 & Get £30 in Free Bets

    18+ New Players only. For free bet wagering requirements and minimum odds read T&C’s. Terms Apply 18+. Full T&C’s Apply. New customers on mobile only. 7 days to claim and stake £10 minimum bet at odds of 1.5 or greater to qualify. Free, void, cashed out or partially cashed out bets do not qualify. Max 3x £10 free bets credited on bet settlement. Free bets must be used on 4 or more selections with selection odds of 1.3 or greater. Free bets are non-withdrawable and stake not returned with winnings. 7 day expiry. Visit Site
  9. Bet £10 Get £30 in Free Bets

  10. Top Odds and over 7,000 Bets Daily – All Sports

    18+ New Players only. For free bet wagering requirements and minimum odds read T&C’s. Terms Apply 18+. T&C Apply Visit Site
Advertiser Disclosure
Every online gambler deserves a safe and fair place to play. Our mission at is to create a safe online environment for players through free, impartial and independent reviews of the UK's best online gambling companies so that you can play with confidence and security. All ratings and reviews are made independently of the operator by our team of gaming experts and with every company being fully UK licensed they can be trusted to offer fair play. We accept compensation from the companies advertised on this page and this may affect the brand positioning. We endeavour to continuously update this list so we can bring you the most current sites and the best available offers but we cannot review every site in the market.

Betting Strategy Articles