Premier League Week 6 Predictions, Odds & EPL Best Bets This Weekend

Date IconLast Updated: Sep 23rd, 2023
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Premier League Week 6 Predictions, Odds & EPL Best Bets This Weekend
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EPL Best Bets & Premier League Week 6 Predictions:


After the first set of fixtures across Europe’s elite competitions, we’re back for another round of EPL best bets from the best online betting sites.

Once again, attention will turn to Manchester United this weekend when it meets with Burnley, who despite being winless so far will fancy its chances at beating the Red Devils - United is +600 with FanDuel to win 2-1.

Luton Town is also aiming for its first win of the season and it will have a great chance to finally win in the Premier League when it hosts Wolverhampton Wanderers - Luton is now +1000 to beat Wolves 1-0 at Caesars.

BetMGM also has odds of +290 for Chelsea to win with 1-0, 2-0 or 3-0, after a tough start for the Blues before their match with Aston Villa.

Our team of experts has looked at the best online betting sites for the hottest Premier League odds and have singled out the EPL best bets for Week 6 action. Also, if you are located in the US states where online sports betting is legal, make sure to sign up with the featured sportsbooks available in your state and claim great bonuses today. 


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Chelsea vs. Aston Villa Premier League Odds & Betting Tips

⭐ Chelsea to win 1-0, 2-0 or 3-0 (+290) at BetMGM

We kick things off for the EPL best bets for Week 6 with our Chelsea vs. Aston Villa prediction that sees the Blues aiming for just their second win of the Premier League season.

After five games, Chelsea has managed to only defeat Luton Town away from home and it has failed to win its past two games as well. However, we expect it to return to winning ways in this one.

Aston Villa has also struggled at times this season and now heads into this game having lost to Liverpool and Newcastle where it has conceded a total of eight goals. What’s more, Chelsea has also not been in midweek European action, unlike Aston Villa, and this will only favor the home team. 

You can also get both teams to score in this game at -163, with both teams scoring in three of the five games involving these two, respectively. 

⭐ EPL Best BetsChelsea to win 1-0, 2-0 or 3-0 (+290) at BetMGM


⭐ CLICK HERE to bet on the Chelsea vs. Aston Villa match! ⭐ 

Brighton vs. Bournemouth Odds & Betting Tips

⭐ Brighton to win and Ferguson to score first (+452) at FanDuel 

What another sensational start to the season it has been for Brighton & Hove Albion. Last weekend, it eased to all three points in another famous win at Old Trafford over Manchester United, beating it 3-1 in the end.

This also means just one loss on the board for Brighton so far after a defeat to West Ham United. With this said, our Brighton vs. Bournemouth prediction heads towards another victory for the home team with Evan Ferguson to score first at +452 with FanDuel.

Ferguson has so far scored four Premier League goals and has been the first goalscorer in one match when he netted a hat-trick against Newcastle United. Against a Bournemouth team without a win this season, Ferguson and Brighton should ease to all three points as part of our EPL picks.

⭐ EPL Best BetsBrighton to win and Ferguson to score first (+452) at FanDuel 


⭐ CLICK HERE to bet on the Brighton vs. Bournemouth match!

Luton Town vs. Wolves Picks, Odds & Betting Tips

⭐ Luton to beat Wolves 1-0 (+1000) at Caesars

Luton Town is still yet to record a win in the Premier League, and it heads into this one hoping that it is the time in which it finally gets off the mark. 

The Hatters fans will be confident in all three points in this game, given how Wolves have scored only five goals, let in 11, lost the same amount of games and won just one match. 

As part of our EPL best bets, our Luton Town vs. Wolves prediction picks a victory for the home team. Luton is at +1000 with Caesars to get the win, and it looks as if this will be the time in which it manages to finally do so.

⭐ EPL Best Bets Luton to beat Wolves 1-0 (+1000) at Caesars


⭐ CLICK HERE to bet on the Luton Town vs. Wolves match! ⭐ 

Burnley vs. Manchester United Prediction Odds & Betting Tips

⭐ United to beat Burnley 2-1 (+600) at DraftKings

Another game goes by meaning another Manchester United defeat, as it lost to Bayern Munich during the week and just four days on from suffering a loss at home to Brighton.  

This game against Burnley should be the perfect chance for United to bounce back with a win, as the Clarets are yet to win a Premier League game since returning to the top flight of English soccer. However, don’t expect it to be a convincing one for United, so our Burnley vs. Manchester United prediction heads towards a narrow win for the Red Devils.

Rasmus Hojlund has also got off to a great start at United, having his goal against Brighton ruled out through VAR before scoring against Bayern Munich during the week - Hojlund is now +400 to score anytime with DraftKings.

Burnley will be confident in getting a win here, however, so our EPL picks opt for both teams scoring but United edging out a narrow win.

⭐ EPL Best BetsUnited to beat Burnley 2-1 (+600) at DraftKings


⭐ CLICK HERE to bet on the Burnley vs. Manchester United match!

Arsenal vs. Tottenham Prediction Odds & Betting Tips

⭐ Arsenal to beat Tottenham and BTTS (+190) at bet365

The first north London derby is upon us this Sunday with Arsenal welcoming Tottenham Hotspur to the Emirates Stadium. So far, both teams remain unbeaten, but Tottenham is ahead of its rivals on goals difference with 13 points each.

The Arsenal vs Tottenham odds favor a win for the home team, and that’s where our EPL picks go. After four games, the Gunners have looked just as impressive as last season and now head into this one having also won 4-0 against the in-form PSV Eindhoven.

Tottenham will, however, likely get a goal after scoring 13 so far and winning four of its five matches. 

⭐ EPL Best BetsArsenal to beat Tottenham and BTTS (+190) at bet365


⭐ CLICK HERE to bet on the Arsenal vs. Tottenham match!

As we look forward to another round of Premier League fixtures, there's another exciting development on the horizon for sports betting enthusiasts. Come this September, Kentucky will be launching online sports betting, paving the way for the emergence of new sports betting apps in Kentucky. This opens up a new realm of opportunities for fans and bettors alike. Stay tuned for more updates on this front.


BetMGM offers a unique Bonus where your first bet can earn you up to $1,500 which can be used to place your bets on the college football season. This means if you place a bet and lose, BetMGM will match the amount (up to $1,500) as free bets in your account, providing another chance to win.

New users need to register, make a first-time deposit, and then simply place their first real-money wager on any FanDuel Sportsbook market that is live on platform. All users will receive their $200 in bonus bets + $100 off NFL Sunday Ticket code within 72 hours of the bet placement.

If the player's qualifying wager is graded as a loss by Caesars, the tarticipant will earn a one-time Bonus Bet token equal to the lesser of (1) the full value of the Qualifying Wager or 2) $1,000 (the “Bonus Bet”).

New users at DraftKings just have to deposit and bet $5 to get $200 instantly and up to $150 in No Sweat Bets. The $200 will be issued in eight $25 bonus bets. Opt-in required for one No Sweat token issued per eligible gameday, up to 3 per week.

The Bet365 bonus is a promotional offer where you can wager $1 and get a $365 bonus. This bonus is credited to your bet365 account and can be used to place further bets, amplifying your potential to win in EPL betting.