College Football Week 6 Picks, Predictions & Best College Football Bets
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College Football Predictions for Week 6:
- ⭐ Missouri Moneyline (+220) at DraftKings
- ⭐ Notre Dame -6.5 (-110) at DraftKings
- ⭐ Georgia -7.5 First Half (-110) at Caesars
- ⭐ Arizona and USC Over 72 points (-110) at FanDuel
College football features some more top matchups in Week 6. There are several top-25 clashes, and CFB Picks spotlights some fun contests in Missouri, Georgia, and much more on Saturday. Besides that, we see what the Irish may do in Louisville. Thankfully, the best college football bets get a look at one of the late games, too.
As always, the best online betting sites include BetMGM, FanDuel, Caesars, and DraftKings. Again, we preview several top-25 games as well as whether Georgia can stay undefeated against Kentucky. Could the Wildcats have a shot against the Bulldogs? Anything seems possible in college football these days. Let’s go to work and search for more dollars in the College Football Week 6 predictions.
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CFB Picks: LSU vs. Missouri Odds & CFB Predictions
⭐ Missouri Moneyline (+220) at DraftKings
The LSU Tigers and Missouri Tigers roar into battle on Saturday afternoon from Missouri. This game is nationally televised on ESPN and is a top choice for CFB Picks weekend. LSU comes in trying to rebound again after a crazy loss against Ole Miss, where it looked like the scoreboard might break. Missouri still is undefeated and looks poised to continue to roll at home. The Midwest Tigers know their road gets even tougher after this week with road games in Kentucky and Georgia.
Free college football picks, enjoy these early afternoon games and do not worry, there’s one coming later this week that is a big one. However, our focus is on the moneyline and not the 6.5-point spread via DraftKings. Missouri is worth at least a field goal alone, which makes the spread a little less fun. The moneyline ranges from +200 to +220 and provides solid value in college football predictions today.
For the LSU vs. Missouri predictions, it is natural to look back at previous years, where the LSU Tigers would be easy favorites. However, times have changed a bit. LSU had a golden opportunity last week at Ole Miss and fumbled it. They are a good team, but at almost a touchdown, even that spread at -110 favors Missouri. Again, Missouri is an entertaining team that has some home magic going for them. LSU’s schedule gets a bit easier from here. Also, Missouri to win and Over at 62.5 points is +450 at FanDuel and worth a second look.
⭐ My best bet: Missouri Moneyline (+220) at DraftKings
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CFB Picks: Notre Dame vs. Lousiville Odds & CFB Predictions
⭐ Notre Dame -6.5 (-110) at DraftKings
Notre Dame and Lousiville are one of those games that would go under the radar if it was not Notre Dame. Yes, college football predictions today see if the Irish can rebound offensively after a couple of sluggish weeks. One week, it resulted in heartbreak, and the next, Notre Dame did survive. With every game a must-win, the Irish can not afford a slip-up in Louisville. After all, that huge USC contest looms in Week 7.
CFB Picks thinks the 6.5-point spread has some value. This will be very close again, and Lousiville will be absolutely ready to play and take their turn with the Irish. This may be another close one-to-two possession game that turns into a possible nailbiter. Louisville did escape against North Carolina State last week, though. Honestly, Notre Dame vs. LSU predictions believe the Irish have what it takes to get the job done.
Notre Dame is learning how to win these big games under Marcus Freeman. Every game is big from here on out. A meaty 6.5-point spread via DraftKings entices another good wager in our college football best bets.
⭐ My best bet: Notre Dame -6.5 (-110) at DraftKings
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CFB Picks: Kentucky vs. Georgia Odds & CFB Predictions
⭐ Georgia -7.5 First Half (-110) at Caesars
Georgia has looked very vulnerable this season. The two-time defending national champions look like anything we have seen in 2023. To be fair, 20th-ranked Kentucky has not played too much quality opposition either. Their SOS (strength of schedule) ranks 128th. However, the Wildcats easily tamed a game Florida Gators squad. Going on the road between the hedges is always different though. Watching Georgia struggle in Auburn on CBS last week was an eye-opener. Free college football picks see if the Bulldogs can get that swagger back before the even rougher opponents come calling.
CFB picks wonder how Carson Beck would do if the Bulldogs can get their running game going a little better. Again, the Bulldogs struggled to run effectively as they won 27-20 at Auburn. When it comes to the 14.5-point spread via Caesars, there is sneaky value at -110. However, the halftime number at 7.5 points is still -110. The expectation is Georgia could make an early statement. Even the Over of 24.5 points (+120 at Caesars) is interesting.
The Wildcats' defense could be walking into a hornet’s nest in Georgia. Kentucky vs. Georgia predictions believe that Georgia can take some of Kentucky’s offense early and get the jump on them. Expect the Bulldogs to get out to a nice halftime lead in our best college football bets for Week 6.
⭐ My best bet: Georgia -7.5 First Half (-110) at Caesars
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CFB Picks: Arizona vs. USC Odds & CFB Predictions
⭐ Arizona and USC Over 72 points (-110) at FanDuel
USC and Caleb Williams know a trip next week to Notre Dame is looming. Do they get caught looking ahead at all? Free college football picks look at if the Trojans can keep covering and score a bunch of points at home on Pac-12 After Dark.
CFB picks take a calculated risk with a whopping 21.5-point spread. They allowed 41 points to Colorado last week after a dominating start. When it comes to that Over of 72 points on FanDuel, that may be where the value lies.
The Arizona offense can rack up some points. Obviously, USC averages almost 54 points a game on the season. Arizona vs. USC predictions believe that the defenses are likely to take a break this week. The amount of points and this game are one of our best college football bets for Week 6.
⭐ My best bet: Arizona and USC Over 72 points (-110) at FanDuel
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Final Words on the College Football Best Bets Today
College Football Week 6 predictions expect the scoreboards and television to get quite a workout on Saturday. Notre Dame (-6.5 at DraftKings) is a great choice to cover, given their desire to close a game out a little earlier this time. For those worried about Notre Dame, Louisville’s strength of schedule ranks 110th out of 133 schools. The best online betting sites highlight these numbers well.
Finally, it is nice to highlight some of the late-night games again. One never quite knows what will happen in USC, as their defense can be a bit of an adventure. There figure to be nervous moments with any 21.5-point spread from FanDuel this Saturday night.
Simply, do not forget those lunchtime games. Those get the table rolling. CFB picks are going to be riled up for this amazing October college football weekend.
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As we look forward to the thrilling College Football matchups for today, there's another exciting development on the horizon for sports betting enthusiasts. As of September 28, Kentucky has officially launched online sports betting, paving the way for the emergence of new Kentucky betting apps. This opens up a new realm of opportunities for fans and bettors alike. Stay tuned for more updates on this front.
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