Kansas City Chiefs at Jacksonville Jaguars NFL Picks, Odds & NFL Week 2 Predictions

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Kansas City Chiefs at Jacksonville Jaguars NFL Picks, Odds & NFL Week 2 Predictions
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NFL Week 2 Predictions & Chiefs vs. Jaguars NFL Picks:


As the 2023 NFL season gets underway, one of the most anticipated matchups is between the Kansas City Chiefs and the Jacksonville Jaguars. 

The Chiefs, despite being the defending Super Bowl champions, are looking to bounce back from a surprising loss to the Detroit Lions. Kansas City's season opener was a forgettable affair, marked by key drops and the absence of star players like tight end Travis Kelce and holdout Chris Jones. However, the team received a boost as Jones ended his holdout and is expected to rejoin the lineup. This is one of the reasons why we have singled out the Chiefs vs. Jaguars matchup, making it one of the best NFL Week 2 Predictions from all 16 games!

On the other hand, the Jaguars are riding high after a comeback win against their divisional rivals, the Indianapolis Colts. Jacksonville, meanwhile, showcased the value of their new acquisition, Calvin Ridley, who proved to be a valuable weapon for quarterback Trevor Lawrence. Their defense also stepped up, limiting Anthony Richardson from having a breakout game. The Jaguars will be looking to carry this momentum into their matchup against the Chiefs and reigning MVP Patrick Mahomes.

 For those seeking expert NFL picks, our Chiefs vs. Jaguars prediction is a must-read.

Whether you're a seasoned bettor or a newcomer to the game, you'll want to consult the best online betting sites for the most reliable NFL Week 2 predictions.

CHECK Out the NFL Week 2 Predictions for All 16 Games!

Chiefs vs. Jaguars Betting Trends & NFL Week 2 Predictions



The NFL Week 2 odds are leaning towards the Bills, with a spread of -9.5 and a moneyline of -435. The over/under is set at 51 points, but given both teams' recent performances, it could be a game with a moderate scoreline, making it one of the NFL best bets for those looking at the under.

How to Watch Chiefs vs. Jaguars

  • Date: Sunday, Sept. 17, 2023
  • Kickoff: 1 p.m. ET
  • Location: TIAA Bank Field — Jacksonville, FL
  • Where to Watch: CBS

After a promising 2-1 preseason record, the Kansas City Chiefs stumbled in their regular-season opener against the Lions, losing 21-20. The team was particularly weak in the second half, getting outscored 14-6. 

Quarterback Patrick Mahomes had an uneven performance, passing for 226 yards and two touchdowns but also throwing an interception. He led the team in rushing with 45 yards, yet the Chiefs were out-gained on the ground 118-90 and struggled with third-down conversions, making just 5 of 14 attempts. 

Despite this setback, the Chiefs have a history of resilience, winning their last eight games following a home loss and covering the spread in their last seven road games after a home defeat. These trends offer valuable insights for making Chiefs vs. Jaguars predictions.

Check Out the Las Vegas Raiders Season Preview HERE!

The Jacksonville Jaguars showcased strong form in the preseason, going undefeated with wins over the Cowboys, Lions, and Dolphins. Their regular-season opener against the Colts was a hard-fought battle, but they managed to overturn a four-point deficit in the fourth quarter to secure a 31-21 victory. Quarterback Trevor Lawrence had a solid outing, throwing for 241 yards, two touchdowns, and an interception, while also rushing for 21 yards. 

Travis Etienne led the ground game with 77 yards and a touchdown, and Calvin Ridley was the top receiver, catching eight passes for 101 yards and a touchdown. However, it's worth noting that the Jaguars have struggled in the first half in 19 of their last 20 games as underdogs against AFC West teams. As they prepare to face the Chiefs, a team with a different caliber, these form indicators and trends are crucial for making informed Chiefs vs. Jaguars NFL Picks.

Chiefs vs. Jaguars Odds & NFL Best Picks

Let's explore some interesting NFL betting trends and look at the Chiefs vs. Jaguars NFL Picks and best  bets:

Chiefs vs. Jaguars Betting Trends:

  • The Jacksonville Jaguars have not hit the Point Spread in 6 of their last 9 games 
  • The Chiefs have won each of their last eight games following a home loss.
  • The Chiefs have covered the spread in each of their last seven road games following a home loss.
  • The total has gone UNDER in 5 of Kansas City's last 6 games against an AFC South 


⭐ NFL Pick 1: Chiefs -3.5 ATS (-110) at BetMGM

The Chiefs are coming off a narrow loss to the Lions, but their track record suggests a strong bounce-back. They've won their last eight games following a home loss and have covered the spread in each of their last seven road games after a home loss. Patrick Mahomes, despite a mixed performance in Week 1, is still a force to be reckoned with. Given these factors, taking the Chiefs to cover the -3.5 spread at BetMGM is a solid bet.

⭐ NFL Pick 2: Under 51.0 total points (-110) at Caesars

The Chiefs and the Jaguars have had inconsistent performances in terms of the Over/Under. Kansas City struggled in the second half against the Lions, getting outscored 14-6, while Jacksonville staged a late-game rally to defeat the Colts. Notably, the total has gone UNDER in five of the Chiefs' last six matchups against teams from the AFC South. Given the defensive strengths displayed by both squads, betting the Under 51.0 at Caesars appears to be a value play.

⭐ NFL Player Prop: Patrick Mahomes Over 303.5 Passing Yards (+105) at FanDuel

Mahomes threw for 226 yards in a lackluster Week 1 performance, but he's poised for a rebound. The Jaguars' defense has been inconsistent, and Mahomes has a history of explosive games. Taking the Over on Mahomes' 303.5 passing yards at FanDuel could yield a profitable outcome.

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As we look forward to the 2023 NFL regular season, there's another exciting development on the horizon for sports betting enthusiasts. Come this September, Kentucky will be launching online sports betting, paving the way for the emergence of new sports betting apps in Kentucky. This opens up a new realm of opportunities for fans and bettors alike. Stay tuned for more updates on this front.


1. How do I get the First bet offer of up to $1,500 on BetMGM?

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2. How do I get the Bet $5 Get $200 in Bonus Bets with Fanduel?

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3. How to claim the Caesars Sportsbook Bet $50 Get $250 in Bonus Bets offer?

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